Article

Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer’s disease cells harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctions

2025-01-10

Abstract excerpt

<h4>ABSTRACT</h4> In addition to small extracellular vesicles known as exosomes, cells release large extracellular vesicles containing mitochondria (EVMs). However, the molecular and functional characteristics of EVMs, as well as the impact of EVM secretion on the spreading of mitochondrial dysfunction between cells, remain unknown in the context of Alzheimer’s Disease (AD). Here, we provide an ultrastructural, b...

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Literature Corpus work: de655a26-f549-5782-b834-e0d49dae9546
DOI: 10.1101/2025.01.08.631851

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Large extracellular vesicles containing mitochondria (EVMs) derived from Alzheimer’s disease cells harbor pathologic functional and molecular profiles and spread mitochondrial dysfunctionsDOI 10.1101/2025.01.08.631851Read

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