Article

Differential interferon-α subtype immune signatures suppress SARS-CoV-2 infection

2021-05-20

Abstract excerpt

<h4>Summary</h4> Type I interferons (IFN-I) exert pleiotropic biological effects during viral infections, balancing virus control versus immune-mediated pathologies and have been successfully employed for the treatment of viral diseases. Humans express twelve IFN-alpha (α) subtypes, which activate downstream signalling cascades and result in distinct patterns of immune responses and differential antiviral respons...

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Literature Corpus work: 63d31517-8cf4-5e5a-8de3-76b524326b76
DOI: 10.1101/2021.05.20.444757

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