Article

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients

2021-03-30

Abstract excerpt

<h4>Summary</h4> The COVID-19 outbreak driven by SARS-CoV-2 has caused more than 2.5 million deaths globally, with the most severe cases characterized by over-exuberant production of immune-mediators, the nature of which is not fully understood. Interferons of the type I (IFN-I) or type III (IFN-III) families are potent antivirals, but their role in COVID-19 remains debated. Our analysis of gene and protein expre...

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Literature Corpus work: 7df66508-f955-5dca-95ae-2fcd6ba7c368
DOI: 10.1101/2021.03.30.437173

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