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Article

Interferon antagonists encoded by SARS-CoV-2 at a glance

2 Apr 2022

Abstract excerpt

The innate immune system is a powerful barrier against invading pathogens. Interferons (IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After recognition of a pathogen by immune sensors, signaling cascades are activated that culminate in the release of IFNs. These activate cells in an autocrine or paracrine fashion eventually setting cells in an anti-viral state via upregulation...

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PMID: 35366686
DOI: 10.1007/s00430-022-00734-9

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