Article

Primed smooth muscle cells acting as first responder cells in disease

2020-10-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Vascular smooth muscle cell (VSMC) dysregulation is a hallmark of vascular disease, including atherosclerosis. In particular, the majority of cells within atherosclerotic lesions are generated from pre-existing VSMCs and a clonal nature has been documented for VSMC-derived cells in multiple disease models. However, the mechanisms underlying the generation of oligoclonal lesio...

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Literature Corpus work: 63c1b724-e107-5f4a-b8fb-4d0652bffc09
DOI: 10.1101/2020.10.19.345769

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