Article

Direct <i>in vivo</i> mapping of functional suppressors in glioblastoma genome

2017-06-22

Abstract excerpt

Glioblastoma (GBM) is one of the deadliest cancers, with limited effective treatments and single-digit five-year survival 1-7 . A causative understanding of genetic factors that regulate GBM formation is of central importance 8-19 . However, a global, quantitative and functional understanding of gliomagenesis in the native brain environment has been lacking due to multiple challenges. Here, we developed an adeno...

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Literature Corpus work: 632c82e7-ae6c-57eb-b633-e112d3438087
DOI: 10.1101/153460

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