Article
Applications of CRISPR-Cas9 Technology to Genome Editing in Glioblastoma Multiforme.
Cells - 7 Sept 2021
Al-Sammarraie Nadia, Ray Swapan K
Abstract excerpt
Glioblastoma multiforme (GBM) is an aggressive malignancy of the brain and spinal cord with a poor life expectancy. The low survivability of GBM patients can be attributed, in part, to its heterogeneity and the presence of multiple genetic alterations causing rapid tumor growth and resistance to conventional therapy. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated (Cas)...
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