Article

Aicardi-Goutières Syndrome gene <i>Rnaseh2c</i> is a metastasis susceptibility gene in breast cancer

2019-02-14

Abstract excerpt

Breast cancer is the second leading cause of cancer-related deaths in the United States, with the majority of these deaths due to metastatic lesions rather than the primary tumor. Thus, a better understanding of the etiology of metastatic disease is crucial for improving survival. Using a haplotype mapping strategy in mouse and shRNA-mediated gene knockdown, we identified Rnaseh2c , a scaffolding protein of the h...

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Identifiers and source

Literature Corpus work: 6321186b-1a25-569f-8fd9-3b2729fff3db
DOI: 10.1101/550418

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