Article

Discovery of a monomeric green fluorescent protein sensor for chloride by structure-guided bioinformatics

2022-07-09

Abstract excerpt

Chloride is an essential anion for all forms of life. Beyond electrolyte balance, an increasing body of evidence points to new roles for chloride in normal physiology and disease. Over the last two decades, this understanding has been advanced by chloride-sensitive fluorescent proteins for imaging applications in living cells. To our surprise, these sensors have been primarily engineered from the green fluorescent...

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Identifiers and source

Literature Corpus work: 631afea1-93e2-55a1-955b-8d1f1b6fdb0a
DOI: 10.1101/2022.07.08.499230

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