The first mutant of the Aequorea victoria green fluorescent protein that forms a red chromophore.

Abstract excerpt

Green fluorescent protein (GFP) from a jellyfish, Aequorea victoria, and its mutants are widely used in biomedical studies as fluorescent markers. In spite of the enormous efforts of academia and industry toward generating its red fluorescent mutants, no GFP variants with emission maximum at more than 529 nm have been developed during the 15 years since its cloning. Here, we used a new strategy of molecular...

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• Amino Acid Sequence
• Color
• Green Fluorescent Proteins
• Microscopy, Fluorescence
• Models, Molecular