Article

RBM-5 modulates U2AF large subunit-dependent alternative splicing in <i>C. elegans</i>

2018-06-25

Abstract excerpt

A key step in pre-mRNA splicing is the recognition of 3’ splicing sites by the U2AF large and small subunits, a process regulated by numerous trans -acting splicing factors. How these trans -acting factors interact with U2AF in vivo is unclear. From a screen for suppressors of the temperature-sensitive (ts) lethality of the C. elegans U2AF large subunit gene uaf-1(n4588) mutants, we identified mutations in th...

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Literature Corpus work: 62ba7442-d4ec-5c63-a010-5faff9944026
DOI: 10.1101/355388

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