Article
The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing.
PLoS genetics - 1 Jan 2012
Ma Long, Gao Xiaoyang, Luo Jintao, Huang Liange, Teng Yanling, Horvitz H Robert
Abstract excerpt
RNA splicing is a major regulatory mechanism for controlling eukaryotic gene expression. By generating various splice isoforms from a single pre-mRNA, alternative splicing plays a key role in promoting the evolving complexity of metazoans. Numerous splicing factors have been identified. However, the in vivo functions of many splicing factors remain to be understood. In vivo studies are essential for understanding...
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