Article

MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells

2021-12-07

Abstract excerpt

<h4> A bstract </h4> MacroH2A variants have been associated with tumor suppression through inhibition of proliferation and metastasis, as well as their role in cellular senescence. However, their role in regulating the dormant state of disseminated cancer cells (DCCs) remains unclear. Here we reveal that solitary dormant DCCs display increased levels of macroH2A variants in head and neck squamous cell carcinoma...

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Literature Corpus work: 62a9c5d4-9f15-5e0f-8f6c-87392ba74dd0
DOI: 10.1101/2021.12.07.471619

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