Article

Metabolic reprogramming tips vaccinia virus infection outcomes by stabilizing interferon-γ induced IRF1

2024-10-11

Abstract excerpt

<h4>ABSTRACT</h4> Interferon (IFN) induced activities are critical, early determinants of immune responses and infection outcomes. A key facet of IFN responses is the upregulation of hundreds of mRNAs termed interferon-stimulated genes (ISGs) that activate intrinsic and cell-mediated defenses. While primary interferon signaling is well-delineated, other layers of regulation are less explored but implied by aberra...

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Literature Corpus work: 628c24d3-5ac3-5897-8c6d-8a8ba0e5c130
DOI: 10.1101/2024.10.10.617691

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