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Rewiring of the host cell metabolome and lipidome during lytic gammaherpesvirus infection is essential for infectious virus production

2023-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Oncogenic virus infections are estimated to cause ∼15% of all cancers. Two prevalent human oncogenic viruses are members of the gammaherpesvirus family: Epstein Barr Virus (EBV) and Kaposi’s Sarcoma Herpesvirus (KSHV). We use murine herpesvirus 68 (MHV-68), which shares significant homology with KSHV and EBV, as a model system to study gammaherpesvirus lytic replication. Viruses implement distin...

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Literature Corpus work
304657a1-8309-55ff-8e11-5fd3a2573f39
DOI
10.1101/2023.01.30.526357
Open publication

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Rewiring of the host cell metabolome and lipidome during lytic gammaherpesvirus infection is essential for infectious virus productionDOI 10.1101/2023.01.30.526357
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