Article

Transcriptional consequences of herpes simplex virus 1 ICP4 inducible expression in uninfected cells

2025-12-09

Abstract excerpt

<h4>ABSTRACT</h4> Successful viral infections reflect the balanced outcome of a tightly regulated program of viral gene expression and manipulation of the host cell environment to favor production of new infectious particles. The productive (lytic) replication cycle of herpes simplex virus 1 (HSV-1) is dependent on the essential transcription factor ICP4 encoded by one of five immediate-early genes. At different...

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Literature Corpus work: 376377a6-a75a-5c04-8bd8-98a68d9aff13
DOI: 10.64898/2025.12.09.693233

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