Article

Precise <i>in vivo</i> functional analysis of DNA variants with base editing using ACEofBASEs target prediction

2021-07-26

Abstract excerpt

Single nucleotide variants (SNVs) are prevalent genetic factors shaping individual trait profiles and disease susceptibility. The recent development and optimizations of base editors, rubber and pencil genome editing tools now promise to enable direct functional assessment of SNVs in model organisms. However, the lack of bioinformatic tools aiding target prediction limits the application of base editing in vivo ....

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Literature Corpus work: 627f676b-d876-5f68-a374-693f28c3de5f
DOI: 10.1101/2021.07.26.453883

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