Article

A Second Photoactivatable State of the Anion-conducting channelrhodopsin GtACR1 empowers persistent activity

2025-03-17

Abstract excerpt

<title>Abstract</title> <p>Optogenetics is a method to regulate cells using light. It is applied to study neurons and to develop diagnostic and therapeutic tools for neuron-related diseases. The cation-conducting channelrhodopsin ChR2 triggers photoinduced depolarization of neuronal cells but generates very low ion currents due to the <italic>syn</italic>-pathway of its branched photocycle. In contrast, the homol...

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Literature Corpus work: 6275b795-4dba-5a02-8204-8f23d08d4702
DOI: 10.21203/rs.3.rs-5677201/v1

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A Second Photoactivatable State of the Anion-conducting channelrhodopsin GtACR1 empowers persistent activityDOI 10.21203/rs.3.rs-5677201/v1Read

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