Article
Proton transfer reactions in the red light-activatable channelrhodopsin variant ReaChR and their relevance for its function.
The Journal of biological chemistry - 25 Aug 2017
Kaufmann Joel C D, Krause Benjamin S, Grimm Christiane, Ritter Eglof, Hegemann Peter, Bartl Franz J
Abstract excerpt
Channelrhodopsins (ChRs) are light-gated ion channels widely used for activating selected cells in large cellular networks. ChR variants with a red-shifted absorption maximum, such as the modified Volvox carteri ChR1 red-activatable channelrhodopsin ("ReaChR," λmax = 527 nm), are of particular interest because longer wavelengths allow optical excitation of cells in deeper layers of organic tissue. In all ChRs...
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