Article
Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond.
Biochemistry - 19 Jan 2010
Bamann Christian, Gueta Ronnie, Kleinlogel Sonja, Nagel Georg, Bamberg Ernst
Abstract excerpt
Channelrhodopsin-2 (ChR2) is a light-gated cation channel and a member of the family of retinylidene photoreceptors. Since the demonstration of light-induced depolarization of ChR2-expressing animal cell membranes, it was increasingly exploited for light triggering of action potentials. ChR2 cond...
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