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Article

Causal relationship between telomere length and osteonecrosis: Bidirectional two-sample Mendelian randomization analysis.

Medicine - 16 Aug 2024

Liu Hao, Yan Wei, Li Jinsong, Luo Di, Yan Dezhi

Abstract excerpt

Recent mounting evidence suggests that shortening of telomere length (TL) is associated with impaired bone health; yet, a genetic causal relationship between TL and osteonecrosis remains uncertain. This study aimed to investigate the potential causal relationship between TL and osteonecrosis using bidirectional two-sample Mendelian randomization (MR). Genome-wide association study summary statistics for TL were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39151532
DOI: 10.1097/MD.0000000000039324
PMCID: PMC11332780

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