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Article

Bone biochemical markers, bone mineral density, and the risk of osteonecrosis of the femoral head: a Mendelian randomization study.

BMC musculoskeletal disorders - 5 Dec 2024

Jia Hai-Feng, Tian Ze-Ming, Liang Xue-Zhen, Li Han-Zheng, Lu Bo-Wen, Zhang Jian, Li Gang

Abstract excerpt

BACKGROUND: Alterations in bone metabolism may play a significant role in the early stages of femoral head necrosis, yet the causal relationship remains unclear. This study utilizes a two-sample Mendelian randomization (MR) approach to explore the genetic causal links between biochemical markers of bone metabolism, bone mineral density, and the risk of femoral head necrosis. METHODS: This study utilizes publicly...

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Alkaline Phosphatase
Biomarkers
Bone Density
Calcium
Femur Head Necrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

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PMID: 39639283
DOI: 10.1186/s12891-024-08130-5
PMCID: PMC11619604

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