Article
Causal relationship between osteoporosis and osteoarthritis: A two-sample Mendelian randomized study.
Frontiers in endocrinology - 1 Jan 2022
Lin Liu, Luo Pan, Yang Mingyi, Wang Jiachen, Hou Weikun, Xu Peng
Abstract excerpt
Introduction: At present, clinical studies have confirmed that osteoporosis (OP) has an inverse relationship with osteoarthritis (OA), but it has not been proven from the point of view of genetics, so our study hopes to clarify the potential effect of OP on OA at the level of gene prediction through two-sample Mendelian randomization (MR) analysis. Methods: A two-sample MR was adopted to research the causal...
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