Article

Temporal dynamics and metagenomics of phosphorothioate epigenomes in the human gut microbiome

2024-05-30

Abstract excerpt

<h4>Background</h4> Epigenetic regulation of gene expression and host defense is well established in microbial communities, with dozens of DNA modifications comprising the epigenomes of prokaryotes and bacteriophage. Phosphorothioation (PT) of DNA, in which a chemically-reactive sulfur atom replaces a non-bridging oxygen in the sugar-phosphate backbone, is catalyzed by dnd and ssp gene families widespread in ba...

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Literature Corpus work: 62059a3c-70ac-512d-ba1c-c950036b4cae
DOI: 10.1101/2024.05.29.596306

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