Article

PT-seq: A method for metagenomic analysis of phosphorothioate epigenetics in complex microbial communities

2024-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Among dozens of known epigenetic marks, naturally occurring phosphorothioate (PT) DNA modifications are unique in replacing a non-bridging phosphate oxygen with redox-active sulfur and function in prokaryotic restriction-modification and transcriptional regulation. Interest in PTs has grown due to the widespread distribution of the dnd, ssp , and brx genes among bacteria and archaea, as well a...

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Literature Corpus work: 49f01143-d372-5c6a-a326-408a53bccc83
DOI: 10.1101/2024.06.03.597111

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