Article

Epigenomic and functional characterization of a core DNA methyltransferase in the human pathogen <i>Clostridium difficile</i>

2018-08-23

Abstract excerpt

Clostridioides difficile is a leading cause of health care-associated infections. Although significant progress has been made in the understanding of its genome, the epigenome of C. difficile and its functional impact has not been systematically explored. Here, we performed the first comprehensive DNA methylome analysis of C. difficile using 36 human isolates and observed great epigenomic diversity. We discovere...

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Literature Corpus work: 4bd936e7-af65-577d-ad11-19a84f3cf9f3
DOI: 10.1101/398891

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