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Article

Mechanisms of action and synergies of a novel lipid IV <sub>A</sub> biosynthesis inhibitor

2023-09-15

Abstract excerpt

The development of novel antimicrobials provides additional treatment options for infectious diseases, including antimicrobial resistant infections. There are many hurdles to antimicrobial development and identifying an antimicrobial’s mechanism of action is a crucial step in progressing candidate molecules through the drug discovery pipeline. We used the genome wide screening method TraDIS- Xpress to identify ge...

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Literature Corpus work
61dc0e2a-8dea-508f-9a72-bdac084f8dc4
DOI
10.1101/2023.09.15.557861
Open publication

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Mechanisms of action and synergies of a novel lipid IV <sub>A</sub> biosynthesis inhibitorDOI 10.1101/2023.09.15.557861
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