Article
Systematic discovery of drug interaction mechanisms.
Molecular systems biology - 29 Apr 2015
Chevereau Guillaume, Bollenbach Tobias
Abstract excerpt
Drug combinations are increasingly important in disease treatments, for combating drug resistance, and for elucidating fundamental relationships in cell physiology. When drugs are combined, their individual effects on cells may be amplified or weakened. Such drug interactions are crucial for treatment efficacy, but their underlying mechanisms remain largely unknown. To uncover the causes of drug interactions, we...
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