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Article

A small molecule that inhibits the evolution of antibiotic resistance

2022-09-26

Abstract excerpt

<h4>Summary</h4> Antimicrobial resistance (AMR) rapidly develops against almost all available therapeutics. New antibiotics target essential processes in bacteria but fail to address the root of the problem: mutagenesis and evolution. We recently proposed that inhibiting the molecular mechanisms underlying bacterial evolution is the ultimate solution to preventing AMR development. Here, we describe the first comp...

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Identifiers and source

Literature Corpus work
717186f5-beed-56ed-b318-d5d75c4802f0
DOI
10.1101/2022.09.26.509600
Open publication

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A small molecule that inhibits the evolution of antibiotic resistanceDOI 10.1101/2022.09.26.509600
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