Article

Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8 <sup>+</sup> T cells in a NOS-dependent manner

2024-06-06

Abstract excerpt

Glioblastoma (GBM) is the most common malignant primary brain tumor, resulting in poor survival despite aggressive therapies. GBM is characterized by a highly heterogeneous and immunosuppressive tumor microenvironment (TME) made up predominantly of infiltrating peripheral immune cells. One significant immune cell type that contributes to glioma immune evasion is a population of immunosuppressive cells, termed myel...

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Literature Corpus work: 61bd4432-3eb2-53f8-a1ce-de42b35d9ff6
DOI: 10.1101/2024.06.05.597474

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Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8 <sup>+</sup> T cells in a NOS-dependent mannerDOI 10.1101/2024.06.05.597474Read

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