Article
The collaborative study on the genetics of alcoholism: Genetics.
Genes, brain, and behavior - 1 Oct 2023
Johnson Emma C, Salvatore Jessica E, Lai Dongbing, Merikangas Alison K, Nurnberger John I, Tischfield Jay A, Xuei Xiaoling, Kamarajan Chella, Wetherill Leah, Rice John P, Kramer John R, Kuperman Samuel, Foroud Tatiana, Slesinger Paul A, Goate Alison M, Porjesz Bernice, Dick Danielle M, Edenberg Howard J, Agrawal Arpana
Abstract excerpt
This review describes the genetic approaches and results from the family-based Collaborative Study on the Genetics of Alcoholism (COGA). COGA was designed during the linkage era to identify genes affecting the risk for alcohol use disorder (AUD) and related problems, and was among the first AUD-focused studies to subsequently adopt a genome-wide association (GWAS) approach. COGA's family-based structure,...
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