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Article

Spatiotemporal Transcriptomes of Pig Hearts Reveal Midkine-Mediated Vascularization in a Chronic Myocardial Infarcted Model

2023-06-11

Abstract excerpt

<h4>ABSTRACT</h4> Ischemic heart disease is the most prevalent cause of death globally. Regenerative cardiology using stem cell-based therapy is a potential approach to replace infarcted myocardial (MI) heart tissue. We used cardiovascular progenitors (CVPs) derived from human pluripotent embryonic stem cells differentiated to cardiomyocyte progenitors on a laminin 521+221 matrix and transplanted them into acute...

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Literature Corpus work
61526738-c6b8-5ff1-beed-570e6c1a002f
DOI
10.1101/2023.06.10.544480
Open publication

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Spatiotemporal Transcriptomes of Pig Hearts Reveal Midkine-Mediated Vascularization in a Chronic Myocardial Infarcted ModelDOI 10.1101/2023.06.10.544480
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