Article

Spatiotemporal Transcriptomics of Human Cardiovascular Progenitors in Pig Hearts Identifies MIDKINE as a Positive Regulator of Neovascularization

2025-01-31

Abstract excerpt

<title>Abstract</title> <p> Stem cell-based therapy has shown promise for regenerating infarcted heart tissue, yet the molecular dynamics and cellular fate of transplanted cells within the myocardium remain largely unexplored. In this study, we used time-series spatial transcriptomics to analyze the global gene expression profile of human pluripotent stem cell-derived cardiovascular progenitors (CVPs) transplant...

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Literature Corpus work: e974d294-ece2-5869-9948-702bd977365a
DOI: 10.21203/rs.3.rs-5837914/v1

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