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PLURIPOTENT STEM CELL-DERIVED CARDIOVASCULAR PROGENITORS DIFFFERENTIATED ON LAMININ 221 REGENERATE AND IMPROVE FUNCTION OF INFARCTED SWINE HEARTS

2021-04-29

Abstract excerpt

<h4>Background</h4> Ischemic heart disease is a huge global burden where patients often have irreversibly damaged heart muscle. State-of-the-art technology using stem cell-derived products for cellular therapy could potentially replace damaged heart muscle for regenerative cardiology. <h4>Methods and Results</h4> Pluripotent human embryonic stem cells (hESCs) were differentiated on a laminin LN521+221 matrix to...

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Literature Corpus work: 128b13b1-9bf8-5879-85fa-0e809712d5a5
DOI: 10.1101/2021.04.29.441908

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