Article

Spatial imprints of emergent cardiomyocyte states in the pressure-overloaded heart

2026-05-08

Abstract excerpt

<h4>Summary</h4> Resilience to cardiac stress is essential for health, yet the relationship between cardiomyocyte (CM) stress response and local microenvironment remains unclear. Here, we combined MERFISH spatial transcriptome profiling with Cellouette , an improved cell segmentation method, to determine CM-microenvironment relationships in a mouse model of ventricular pressure overload. We report the shape, tra...

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Literature Corpus work: 8c7b7278-2c2a-5b6a-b2ee-b49f76aa716f
DOI: 10.64898/2026.05.04.721738

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