Article

Micropatterned Organoids Enable Modeling of the Earliest Stages of Human Cardiac Vascularization

2022-07-10

Abstract excerpt

Although model organisms have provided insight into the earliest stages of cardiac vascularization, we know very little about this process in humans. Here we show that spatially micropatterned human pluripotent stem cells (hPSCs) enable in vitro modeling of this process, corresponding to the first three weeks of in vivo human development. Using four hPSC fluorescent reporter lines, we create cardiac vascular org...

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Literature Corpus work: 9cf900ab-7f6a-5bad-a9e8-361180394cbe
DOI: 10.1101/2022.07.08.499233

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