Article

Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma

2022-04-12

Abstract excerpt

The tumor micro-environment (TME) of hepatocellular carcinoma (HCC) consists out of cirrhotic liver tissue and is characterized by an extensive deposition of extracellular matrix proteins (ECM). The evolution from a reversible fibrotic state to end-stage of liver disease, namely cirrhosis, is characterized by an increased deposition of ECM, as well as changes in the exact ECM composition, which both contribute to...

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Literature Corpus work: 614a4fdb-07ff-5d27-8cca-695d31a3c9ad
DOI: 10.21203/rs.3.rs-1537560/v1

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