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Article

Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells

2023-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Non-alcoholic fatty liver disease affects 30% of the United States population and its progression can lead to non-alcoholic steatohepatitis (NASH), which can result in cirrhosis and hepatocellular carcinoma. NASH is characterized by a highly heterogeneous liver microenvironment created by the fibrotic activity of hepatic stellate cells (HSCs). While HSCs have been widely studied in 2D, further a...

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Literature Corpus work
d3ecfbba-a5a2-5e13-b4b5-abf1c1262829
DOI
10.1101/2023.05.05.539608
Open publication

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Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate CellsDOI 10.1101/2023.05.05.539608
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