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Interaction between <em>M. tuberculosis</em> Lineage and Human Genetic Variants Reveals Novel Pathway Associations With Severity of TB

2021-10-04

Abstract excerpt

Tuberculosis (TB) remains a major public health threat globally, especially in sub-Saharan Africa. Both human and Mycobacterium tuberculosis (MTBC) genetic variation affect TB outcomes, but few studies have examined if and how the two genomes interact to affect disease. We hypothesize that long-term coexistence between human genomes and MTBC lineages modulate disease to affect its severity. We examined this hypoth...

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Identifiers and source

Literature Corpus work
6135ad21-8af0-5252-9883-c9408338b205
DOI
10.20944/preprints202110.0045.v1
Open publication

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Interaction between <em>M. tuberculosis</em> Lineage and Human Genetic Variants Reveals Novel Pathway Associations With Severity of TBDOI 10.20944/preprints202110.0045.v1
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