Article

Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from Tanzania

2023-05-11

Abstract excerpt

The risk and prognosis of tuberculosis (TB) are affected by both human and bacterial genetic factors. To identify interacting human and bacterial genetic loci, we leveraged paired human and Mycobacterium tuberculosis ( M . tb ) genomic data from 1000 Tanzanian TB patients. Through a genome-to-genome approach, we identified two pairs of human and M . tb genetic variants that are significantly associated. One of the...

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Literature Corpus work: 3bfe323f-06ee-5286-874f-e1decc2732f3
DOI: 10.1101/2023.05.11.23289848

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