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The Interplay of Human and Mycobacterium Tuberculosis Genomic Variability

18 Sept 2019

Abstract excerpt

Tuberculosis (TB), caused by the human pathogens Mycobacterium tuberculosis (Mtb) and Mycobacterium africanum, has plagued humanity for millennia and remains the deadliest infectious disease in the modern world. Mtb and M. africanum can be subdivided phylogenetically into seven lineages exhibiting a low but significant degree of genomic diversity and preferential geographic distributions. Human genetic...

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PMID: 31620169
DOI: 10.3389/fgene.2019.00865

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