Article

Endogenous gene tagging with FnCas9 to track and sort neural lineages from 3D cortical organoids

2025-01-13

Abstract excerpt

Neural lineage tracing, or molecular dissection of lineage-specific brain cell types, is used in many labs to learn how neurons grow and mature. However, these studies depend on the growth and characterization of pure cultures, which takes a long time because of biochemical or fluorescence-based isolation through cell surface markers that overlap. These lineage-specific cells, however, can be efficiently sorted us...

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Literature Corpus work: 6126544a-879a-5a2c-b60f-697b11c881a4
DOI: 10.1101/2025.01.09.631995

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