Article
Analysis of in vitro and in vivo characteristics of human embryonic stem cell-derived neural precursors.
Cell transplantation - 1 Jan 2010
Kozubenko Nataliya, Turnovcova Karolina, Kapcalova Miroslava, Butenko Olena, Anderova Miroslava, Rusnakova Vendula, Kubista Mikael, Hampl Ales, Jendelova Pavla, Sykova Eva
Abstract excerpt
During the last decade, much progress has been made in developing protocols for the differentiation of human embryonic stem cells (hESCs) into a neural phenotype. The appropriate agent for cell therapy is neural precursors (NPs). Here, we demonstrate the derivation of highly enriched and expandable populations of proliferating NPs from the CCTL14 line of hESCs. These NPs could differentiate in vitro into...
Topics
- Animals
- Biomarkers
- Brain
- Cell Differentiation
- Cell Line
- Cell Lineage
- Cell- and Tissue-Based Therapy
- Embryonic Stem Cells
- Flow Cytometry
- Humans
- Immunohistochemistry
