Article
Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs).
Journal of visualized experiments : JoVE - 2 Mar 2018
Williams Madeline, Prem Smrithi, Zhou Xiaofeng, Matteson Paul, Yeung Percy Luk, Lu Chi-Wei, Pang Zhiping, Brzustowicz Linda, Millonig James H, Dicicco-Bloom Emanuel
Abstract excerpt
Human brain development proceeds through a series of precisely orchestrated processes, with earlier stages distinguished by proliferation, migration, and neurite outgrowth; and later stages characterized by axon/dendrite outgrowth and synapse formation. In neurodevelopmental disorders, often one or more of these processes are disrupted, leading to abnormalities in brain formation and function. With the advent of...
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