Article

<i>DCX</i> knockout ferret reveals a neurogenic mechanism in cortical development

2024-06-13

Abstract excerpt

<h4>SUMMARY</h4> Doublecortin (DCX) is one of the major causal proteins leading to lissencephaly and subcortical band heterotopia in human patients. However, our understanding of this disease, as well as the function of DCX during neurogenesis, remains limited due to the absence of suitable animal models that accurately represent human phenotypes. Here, we conducted a comprehensive examination of the neocortex at...

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Literature Corpus work: 84fc923e-355a-560a-aefb-f661771bef0f
DOI: 10.1101/2024.06.13.598795

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