Article

Mendelian Randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

2018-10-19

Abstract excerpt

<h4>Background</h4> Fibrinogen is an essential hemostatic factor and cardiovascular disease risk factor. Early attempts at evaluating the causal effect of fibrinogen on coronary heart disease (CHD) and myocardial infraction (MI) using Mendelian randomization (MR) used single variant approaches, and did not take advantage of recent genome-wide association studies (GWAS) or multi-variant, pleiotropy robust MR metho...

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Literature Corpus work: 611a699d-b9e9-56dc-bbcf-7c478cc7b4f3
DOI: 10.1101/448381

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