Article

From Genomics Data to Causality: An Integrated Pipeline for Mendelian Randomization

2023-11-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mendelian randomization (MR) has emerged as a valuable tool for causal inference in genetic epidemiology. Existing MR methods have issues related to pleiotropy and offer limited comprehensiveness. Here, we introduce an integrated MR analysis pipeline designed for GWAS summary statistics data. Our pipeline integrates feature selection, harmonization, and checkpoint mechanisms t...

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Literature Corpus work: bfba9042-9ede-5d65-8bbc-941f582ab4a9
DOI: 10.1101/2023.11.04.23298053

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