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Article

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'.

International journal of epidemiology - 1 Aug 2006

Keavney Bernard, Danesh John, Parish Sarah, Palmer Alison, Clark Sarah, Youngman Linda, Delépine Marc, Lathrop Mark, Peto Richard, Collins Rory

Abstract excerpt

BACKGROUND: Blood concentrations of fibrinogen have been associated with coronary heart disease risk in epidemiological studies, but it is uncertain whether this association is causal or reflects residual confounding by other risk factors. We investigated the relationship between the single nucleotide polymorphism at position -148 in the beta-fibrinogen gene promoter (beta - 148C/T), blood fibrinogen levels, and...

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Identifiers

PMID: 16870675
DOI: 10.1093/ije/dyl114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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