Article
Mendelian Randomization for the Identification of Causal Pathways in Atherosclerotic Vascular Disease.
Cardiovascular drugs and therapy - 1 Feb 2016
Jansen Henning, Lieb Wolfgang, Schunkert Heribert
Abstract excerpt
Epidemiological and clinical studies have identified many physiological traits and biomarkers that are statistically associated with coronary artery disease (CAD). For some of these traits and biomarkers it is well established that they represent true causal risk factors for CAD. For other biomarkers, however, the distinct character of association is still a matter of debate. Randomized controlled trials (RCT)...
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