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A Kmer-based paired-end read (KPR) <i>de novo</i> assembler and genotyper to genotype major histocompatibility complex class I (MHC-I) alleles for the dog

2020-07-17

Abstract excerpt

The major histocompatibility complex class I (MHC-I) genes are highly polymorphic among individuals. MHC-I genotyping is required for determining the antigen-binding specificity of each MHC-I molecule in an individual. Numerous tools have been developed for human MHC-I genotyping using deep sequencing data such as RNA-seq; however they do not work for the dog, due to very limited information for canine alleles. To...

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Identifiers and source

Literature Corpus work
6055a729-b098-5eb1-922e-e9012c009b05
DOI
10.1101/2020.07.15.205559
Open publication

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